The frequency of pathogenic variation in the All of Us cohort reveals ancestry-driven disparities | Communications Biology
Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA
Eric Venner, Divya Kalra, Yi-Ju Chen, Sara E. Kalla, Bo Yuan, Kimberly Walker, Qiaoyan Wang & Richard A. Gibbs
Department of Genome Sciences, University of Washington, Seattle, WA, USA
Karynne Patterson, Marsha M. Wheeler, Joshua D. Smith, Sean McGee & Aparna Radhakrishnan
University of Arizona, R Ken Coit College of Pharmacy, Department of Pharmacy Practice and Science, Tucson, AZ, USA
Jason H. Karnes
Vanderbilt University Medical Center, Department of Biomedical Informatics, Boston, MA, USA
Jason H. Karnes
Department of Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy, Pittsburgh, PA, USA
Andrew Haddad
Department of Pharmacy and Therapeutics, University of Pittsburgh School of Pharmacy, Pittsburgh, PA, USA
Philip E. Empey
Broad Institute of MIT and Harvard, Cambridge, MA, USA
Lee Lichtenstein & Diana Toledo
Department of Medicine (Medical Genetics), University of Washington School of Medicine, Seattle, WA, USA
Gail Jarvik
Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA, USA
Gail Jarvik
NIH All of Us Research Program, National Institutes of Health Office of the Director, Bethesda, MD, USA
Anjene Musick
Henry Ford Health System, Detroit, MI, USA
Brian Ahmedani, Christine D. Cole Johnson & Cathryn Peltz-Rauchman
University of Chicago Medical Center, Chicago, IL, USA
Habib Ahsan
University of California, Irvine - Irvine, California, CA, USA
Hoda Anton-Culver
Scripps Research Translational Institute - La Jolla, California, CA, USA
Eric Topol, Katie Baca-Motes, Julia Moore-Vogel & Evan Muse
Vibrent Health, Fairfax, VA, USA
Praduman Jain, Mark Begale, Neeta Jain, David Klein & Scott Sutherland
University of Alabama at Birmingham, Birmingham, AL, USA
Bruce Korf & Beth Lewis
Columbia University - New York City, New York, NY, USA
Ali G. Gharavi & George Hripcsak
University of Texas Health Science Center at Houston, Houston, TX, USA
Eric Boerwinkle & David McPherson
Marshfield Clinic Research Institute, Marshfield, WI, USA
Scott Joseph Hebbring & Sanjay Skukla
University of Wisconsin at Madison, Madison, WI, USA
Elizabeth Burnside & Dorothy Farrar-Edwards
Community Health Center, Inc., Middletown, CT, USA
Amy Taylor & Katrina Yamazaki
Sun River Health - Beacon, New York, NY, USA
Liliana Lombardi Desa & Kathleen Keogh
Mayo Clinic and Foundation, Rochester, MN, USA
Steve Thibodeau & Mine Cicek
Cooperative Health, South Carolina, SC, USA
Eric Schlueter & Beverly Wilson Holmes
University of Illinois at Chicago, Evanston, IL, USA
Martha Daviglus, Maria Argos & Brisa Aschebook-Kilfoy
Vanderbilt University Medical Center, Nashville, TN, USA
Paul Harris, Consuelo Wilkins, Dan Roden & Melissa Basford
Johns Hopkins University School of Medicine, Baltimore, MD, USA
Kim Doheny
University of Washington, Seattle, Washington, WA, USA
Evan Eichler & Gail Jarvik
FiftyForward, Nashville, TN, USA
Gretchen Funk
Broad Institute - Boston Massachusetts, Boston, USA
Anthony Philippakis, Heidi Rehm, Stacey Gabriel & Niall Lennon
Baylor College of Medicine, Houston, TX, USA
Richard Gibbs, Brendan Lee & Laura Rosales
National Alliance for Hispanic Health, Washington, DC, USA
Edgar M. Gil Rico & Adolph Falcon
Verily Life Sciences - South San Francisco, California, CA, USA
David Glazer
MITRE Corporation, McLean, VA, USA
Jessica Burke
Northwestern University, Evanston, IL, USA
Philip Greenland & Joyce Ho
University of Florida, Gainesville, FL, USA
Elizabeth Shenkman, William R. Hogan & Eileen Handberg
Morehouse School of Medicine, Atlanta, GA, USA
Priscilla Igho-Pemu & Robert Meller
Partners Health Care - Boston, Massachusetts, MA, USA
Elizabeth W. Karlson, Jordan Smoller & Shawn N. Murphy
Cornell University, Weill Medical College - New York City, New York, NY, USA
Margaret Elizabeth Ross & Rainu Kaushal
Cherokee Health Systems, Knoxville, TN, USA
Eboni Winford, Gail Reilly, Kyla Taylor & Daniel Hernandez Tinoco
CareEvolution, Inc, Ann Arbor, MI, USA
Vik Kheterpal
University of Arizona, Tucson, Tucson, AZ, USA
Francisco A. Moreno
Delta Research and Educational Foundation, Washington, DC, USA
Cheryl Thomas
Stanford University - Stanford, California, CA, USA
Mitchell Lunn & Juno Obedin-Maliver
University of Pittsburgh, Pittsburgh, PA, USA
Oscar Marroquin, Shyam Visweswaran & Steven Reis
Wondros - Los Angeles, California, CA, USA
Patrick McGovern
San Ysidro Health Center - San Ysidro, California, CA, USA
Gregory Talavera & Linda Salgin
Boston Medical Center - Boston, Massachusetts, MA, USA
George T. O’Connor
University of California, San Diego – San Diego, California, CA, USA
Lucila Ohno-Machado, Amy Sitapati & Amaryllis Silva Boschetti
Asian Health Coalition, Chicago, IL, USA
Fornessa Randal
Banner Health, Phoenix, AZ, USA
Andreas A. Theodorou & Eric Reiman
Montage Marketing Group, Rockville, MD, USA
Mercedita Roxas-Murray
University of Utah, Salt Lake City, Utah, USA
Louisa Stark
HCM Strategists, Austin, TX, USA
Ronnie Tepp
Color Genomics, Inc. – Burlingame, California, CA, USA
Alicia Zhou & Scott Topper
NYC Health + Hospitals - New York City, New York, NY, USA
Rhonda Trousdale
VA AoU Coordinating Center - Palo Alto, California, CA, USA
Phil Tsao
Brigham and Women’s Hospital – Boston, Massachusetts, MA, USA
Scott T. Weiss & Cheryl Clark
Medical College of Wisconsin, Milwaukee, WI, USA
Jeffrey Whittle & Zeno Frano
University of Miami School of Medicine, Miami, FL, USA
Stephan Zuchner, Olveen Carrasquillo, Rosario Isasi & Jacob McCauley
Research Triangle Institute - Research Triangle Park, Raleigh, NC, USA
Megan Lewis & Jen Uhrig
Waianae Coast CHC, Waianae, HI, USA
May Okihiro & Emily Makahi
National Library of Medicine (NLM), Bethesda, MD, USA
Laura Bartlett
American Association of Health and Disability, Sedona, AZ, USA
Roberta Carlin, Karl Cooper & Charles Drum
Hunter College - New York City, New York, NY, USA
Elizabeth Cohn & Frida Kleiman
University of Puerto Rico Comprehensive Cancer Center, San Juan, WA, USA
Vivian Colon-Lopez & Jose Melo
CTSA Community Engagement Programs, Gainesville, FL, USA
Linda Cottler & Milton Eder
University of South Alabama, Mobile, AL, USA
Errol Crook
TPC: Blood Assurance - Signal Mountain, Tennessee, TN, USA
Elizabeth Culler
San Diego Blood Bank – San Diego, California, CA, USA
Mark Edmunds
TPC: Denver Health - Denver, Colorado, CO, USA
Rachel Everhart
TPC: Active Minds -, Washington, DC, USA
Becky Fein & Laura Horne
University of Mississippi Medical Center, Jackson, MS, USA
Michael Garrett & Babbette Lamarca
TPC: DLH Corp, Atlanta, GA, USA
Sandra Halverson
Mass General Hospital - Boston, Massachusetts, MA, USA
Jessica Isom, Cynthia So-Armah & Paul Nemeskal
Tactis -, Washington, DC, USA
Jessica Jarmin
TPC: Mary’s Center -, Washington, DC, USA
Megan Jula
TPC: Owaves -, Washington, DC, USA
Royan Kamyar
Harvard Medical School - Boston, Massachusetts, MA, USA
Isaac Kohane
National Baptist Convention, Nashville, TN, USA
Dessie Levy & Michael Minor
Gundersen Health System, La Crosse, WI, USA
Todd Mahr
South Texas Blood and Tissue Center, San Antonio, TX, USA
Vivienne Marshall
University of North Carolina at Chapel Hill - Chapel Hill, Chapel Hill, NC, USA
Elizabeth Mayer-Davis
Sensis - Glendale, California, CA, USA
Jeffrey McKinney & Jamie Walz
TPC: Bloodworks Northwest – Seattle, Washington, WA, USA
David Ming-Hung Lin
TPC: Fitbit - San Francisco, California, CA, USA
Kapil Parakh
COSSMA, Aibonito, PR, Puerto Rico
Linda Perez Laras & Nelida Rivera
Patients Like Me, Houston, TX, USA
Subhara Raveendran
Quest Diagnostics Incorporated – Secaucus, Secaucus, NJ, USA
Jody Reilly & Yuri Fresko
Emory University, Atlanta, GA, USA
Tracie Rosser, Suchitra Chandrasekaran, Robert Kelley, Matt Pagel & Miriam Vos
VA AoU Coordinating Center - Boston, Massachusetts, MA, USA
Sherilyn Sawyer & Jason Vassy
Cascade Regional Blood Services - Tacoma, Washington, WA, USA
William Simonson
ExamOne, Mission, KS, USA
Gene Stegeman
Sage Bionetworks – Seattle, Washington, WA, USA
Christin Suver
Walgreen Co., Deerfield, IL, USA
Michael Taitel
WebMD Health Corp – New York City, New York, NY, USA
Preston Watkins
Blue Cross Blue Shield, Chicago, IL, USA
Blaker Wilkerson
Saint Louis University, Saint Louis, MO, USA
Matthew Breeden, Kim Enard, Richard Grucza, Ted Malmstrom & Jeffrey Scherrer
Mount Sinai Health System - New York City, New York, NY, USA
Monica Kraft
LifeSouth, Gainesville, FL, USA
Christopher Lough
SunCoast Blood Center, Bradenton, FL, USA
Debra Smith
University Southern California - Los Angeles, California, CA, USA
Bryce Turner
Conceived and designed the analysis: E.V., A.M., R.G., G.J., P.E. Collected the data: E.V., D.K., K.P., M.W., Y.C., L.L. Performed the analysis: E.V., K.P., D.K., M.W., Y.C. Wrote the paper: E.V., K.P., D.K., M.W., Y.C., S.K., B.Y., J.K., K.W., J.S., S.M., A.R., A.H., P.E., Q.W., L.L., D.T., G.J., A.M., R.G.