Nets vs. Celtics odds, line, spread: 2021 NBA picks, Nov. 24 predictions from model on 115-76 roll

The Brooklyn Nets put an impressive road record on the line in a challenging spot on Wednesday. Brooklyn is 7-2 away from home and 13-5 overall this season, and the Nets will visit the Boston Celtics at TD Garden. Boston is 10-8 overall and 5-3 in home tilts. Jaylen Brown (reconditioning), Robert Williams III (illness) and Josh Richardson (illness) are questionable to play for the Celtics. Kyrie Irving remains out for Brooklyn, with Joe Harris (ankle), Bruce Brown (hamstring) and Nicolas Claxton (illness) also out for the Nets.

Caesars Sportsbook lists Brooklyn as a one-point road favorite, and tip-off is scheduled for 7:30 p.m. ET. The total number of points Vegas thinks will be scored, or the over-under, is 216 in the latest odds. Before you make any Nets vs. Celtics picks and NBA predictions, see what SportsLine's advanced computer model has to say.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $9,000 in profit on its top-rated NBA picks over the past three-plus seasons. The model enters Week 6 of the 2021-22 NBA season up over $1,200 on all top-rated NBA picks this season. It's also on a stunning 115-76 roll on top-rated NBA picks against the spread that dates back to last season. Anyone following it has seen huge returns.

Now, the model has set its sights on Nets vs. Celtics. You can head to SportsLine to see its picks. Now, here are several NBA odds, betting lines and trends for Celtics vs. Nets:

• Nets vs. Celtics spread: Nets -1
• Nets vs. Celtics over-under: 216 points
• Nets vs. Celtics money line: Nets -110, Celtics -110
• Brooklyn: The Nets are 7-10-1 against the spread in the last 18 games
• Boston: The Celtics are 10-7-1 against the spread in the last 18 games

Why the Nets can cover

Brooklyn's defense has been one of the breakout stories of the season, with the Nets ranking in the top 10 of the NBA in defensive efficiency. Opponents are scoring only 105.5 points per 100 possessions against Brooklyn this season, and that includes 42.8 percent shooting and only 31.1 percent from three-point range. The Nets are also a top-six team in assists allowed (21.7 per game), and Brooklyn is playing a Boston team that is below-average in overall shooting efficiency with 44.3 percent from the floor and 33.3 percent from three-point distance. 

The Nets are highly explosive on offense, with Kevin Durant and James Harden leading the way. Durant is averaging 28.5 points, 7.8 rebounds and 5.1 assists per game, with Harden adding 20.8 points, 9.1 assists and 7.6 rebounds per contest this season. Few teams can match that dual firepower, with the Nets also shooting 37.6 percent from three-point range to lead the NBA.

Why the Celtics can cover

Boston is very potent on the defensive end, giving up only 105.3 points per 100 possessions. The Celtics are No. 6 in the NBA in defensive efficiency, with a top-tier defensive rebound rate of 79 percent. Opponents are shooting just 43.4 percent from the floor against Boston, with the Celtics yielding only 21.2 assists per game. Boston is above-average in steals (7.9 per game) and blocks (5.7 per game), and Brooklyn is currently the worst offensive rebounding team in the NBA. 

On the opposite end, Jayson Tatum leads the way in averaging 25.7 points along with 8.4 rebounds per game, and Boston is a top-seven team in free throw attempts (20.7 per game) and free throw accuracy (80.6 percent). The Celtics take care of the ball at a high level, committing a turnover on only 12.5 percent of possessions, and Brooklyn is forcing only 13.4 turnovers per game in 2021-22.

How to make Nets vs. Celtics picks

SportsLine's model is leaning over on the total, with three players projected to score more than 22 points. The model also says one side of the spread hits in almost 60 percent of simulations. You can only get the pick at SportsLine.

So who wins Celtics vs. Nets? And which side of the spread hits in almost 60 percent of simulations? Visit SportsLine now to find out which side of the Nets vs. Celtics spread you need to jump on Wednesday, all from the model that has crushed its NBA picks, and find out.